Syed Ahmed Shah

Assistant Professor

Faculty of Pharmacy

Research on stimuli-responsive hydrogels for clinical applications

Ahmed possesses comprehensive knowledge and skills in the synthesis, intro, and in vivo evaluation of biomaterials for drug delivery and biomedical applications. His scientific research focused on the development, characterization, and in vivo evaluation of stimuli-responsive hydrogels for diversified biomedical applications. Key areas of research are centered on enzymatically crosslinked hydrogels and pH-responsive hydrogels for […]

Ahmed possesses comprehensive knowledge and skills in the synthesis, intro, and in vivo evaluation of biomaterials for drug delivery and biomedical applications. His scientific research focused on the development, characterization, and in vivo evaluation of stimuli-responsive hydrogels for diversified biomedical applications. Key areas of research are centered on enzymatically crosslinked hydrogels and pH-responsive hydrogels for […]

  1. Abbasi, M., Sohail, M., Shah, S. A., Qalawlus, A. H. M., & Farhana, S. A. (2025). Chondroitin Sulphate-based hydrogels loaded with folic acid-functionalized nanoparticles to target colorectal cancer. Journal of Drug Delivery Science and Technology, 107479.
  2. Shah, S. A., Sohail, M., Nakielski, P., Rinoldi, C., Zargarian, S. S., Kosik-Kozioł, Ziai, Y., Haghighat Bayan, M.A., Zakrzewska, A., Rybak, D. Bartolewska, M., & Pierini, F. 2024. Integrating Micro-and Nanostructured Platforms and Biological Drugs to Enhance Biomaterial-Based Bone Regeneration Strategies. Biomacromolecules. Corresponding author
  3. Zargarian, S., Zakrzewska, A., Kosik-Kozioł, A., Bartolewska, M., Shah, S. A., Li, X., Su, Q., Petronella, F., Marinelli, M., De Sio, L., Lanzi, M., Ding, B. & Pierini, F. 2024. Advancing Resource Sustainability with Green Photothermal Materials: Insights from Organic Waste-Derived and Bio-Derived Sources. Nanotechnology Reviews, 13(1), 20240100.
  4. Haghighat Bayan, M.A., Rinoldi, C., Kosik‐Kozioł, A., Bartolewska, M., Rybak, D., Zargarian, S.S., Shah, S.A., Krysiak, Z.J., Zhang, S., Lanzi, M. and Nakielski, P., 2024. Solar‐to‐NIR Light Activable PHBV/ICG Nanofiber‐Based Face Masks with On‐Demand Combined Photothermal and Photodynamic Antibacterial Properties. Advanced Materials Technologies, p.2400450.
  5. Kashif, M. U., Sohail, M., Mahmood, A., Shah, S.A., Abbasi, M., & Kousar, M. 2024. Nose-to-brain delivery of nano-engineered biomaterials for effective targeting to the brain. International Journal of Polymeric Materials and Polymeric Biomaterials, 1-24.
  6. Jabeen, N., Sohail, M., Mahmood, A., Shah, S.A., Qalawlus, A.H.M., Khaliq, T., 2024. Nanocrystals loaded collagen/alginate-based injectable hydrogels: A promising biomaterial for bioavailability improvement of hydrophobic drugs. Journal of Drug Delivery Science and Technology, 91, 105291
  7. Haroon, B., Sohail, M., Minhas, M. U., Mahmood, A., Hussain, Z., Shah, S.A., Khan, S., M., Abbasi, M., Kashif, M. R. 2023. Nano-residronate loaded κ-carrageenan-based injectable hydrogels for bone tissue regeneration. International Journal of Biological Macromolecules, 251, 126380.
  8. Farooq, T., Sohail, M., Shah, S.A., Mahmood, A., Qalawlus, A.H.M., Kashif, M.R., Kousar, M., 2023. Colloidal curcumin-laden pH-responsive hydrogels: A promising approach to enhance solubility, dissolution, and permeation of hydrophobic drug. Journal of Drug Delivery Science and Technology, 84, 104471.
  9. Abbasi, M., Sohail, M., Minhas, M., Mahmood, A., Shah, S.A., Munir, A., Kashif, M.R., 2023. Folic acid-decorated alginate nanoparticles loaded hydrogel for the oral delivery of diferuloylmethane in colorectal cancer. International Journal of Biological Macromolecules, 233, 123585.
  10. Shah, S.A., Sohail, M., Karperien, M., Johnbosco, C., Mahmood, A., Kousar, M., 2023. Chitosan and carboxymethyl cellulose-based 3D multifunctional bioactive hydrogels loaded with nano-curcumin for synergistic diabetic wound repair. International Journal of Biological Macromolecules, 227, 203-220.
  11. Jabeen, N., Sohail, M., Shah, S.A., Mahmood, A., Kashif, M. R., Khaliq, T., 2022. Silymarin nanocrystals-laden chondroitin sulfate-based thermoreversible hydrogels; A promising approach for bioavailability enhancement. International Journal of Biological Macromolecules, 218, 456-472.
  12. Kashif, M. R., Sohail, M., Khan, S.A., Minhas, M. Mahmood, A., Shah, S.A., Mohsin, S., 2022. Chitosan/guar gum-based thermoreversible hydrogels loaded with pullulan nanoparticles for enhanced nose-to-brain drug delivery. International Journal of Biological Macromolecules, 215, 579-595.
  13. Khaliq, T., Sohail, M., Shah, S.A., Mahmood, A., Kousar, M., Jabeen, N., 2022. Bioactive and multifunctional keratin-pullulan-based hydrogel membranes facilitate re-epithelization in diabetic models. International Journal of Biological Macromolecules, 2022, 209, 1826-1836 (IF. 8.025)
  14. Ijaz, U., Sohail, M., Minhas, M. U., Khan, S., Hussain, Z., Kazi, M., Shah, S.A., Mahmood, A., Maniruzzaman, M., 2022. Biofunctional Hyaluronic acid/κ‐carrageenan injectable hydrogels for improved drug delivery and wound healing. Polymers, 14, 376-385.
  15. Khaliq, T., Sohail, M., Minhas, M. U., Shah, S.A., Jabeen, N., Khan, S., Hussain, Z., Mahmood, A., Kousar, M., Rashid, H., 2021. Self-crosslinked chitosan/ κ- carrageenan-based biomimetic membranes to combat diabetic wound infections. International Journal of Biological Macromolecules, 197, 157-168.
  16. Shah, S.A., Sohail, M., Minhas, M. U., Khan, S., Hussain, Z., Kousar, M., Abbasi, M., Kashif, M. R., Hanin, E. T. 2021. Curcumin-laden hyaluronic acid-co-pullulan-based biomaterials as a potential platform to synergistically enhance diabetic wound repair. International Journal of Biological Macromolecules, 185, 350-368.
  17. Shah, S.A., Sohail, M., Khan, S.A., Kousar, M. 2021. Improved drug delivery and accelerated diabetic wound healing by chondroitin sulfate-g-alginate-based thermoreversible hydrogels. Materials Science and Engineering: C 126, 112-169.
  18. Shafique, M., Sohail, M., Minhas, M. U., Khaliq, T., Kousar, M., Khan, S., Hussain, Z., Abbasi, M., Heather, C. Aziz., Shah, S.A., 2020. Bio-functional Hydrogel Membranes Loaded with Chitosan Nanoparticles for Accelerated Wound Healing. International Journal of Biological Macromolecules, 170, 207-221.
  19. Zia, A., Sohail, M., Minhas, M. U., Rai, M. S., Khan, S., Hussain, Z., Abbasi, M., Shah, S.A., & Kousar, M. 2019. PHEMA-based pH-sensitive semi-IPN microgels for oral delivery: A rationale approach for Ketoprofen. Drug Development and Industrial Pharmacy, 46, 272-282.
  20. Shah, S. A., Sohail, M., Minhas, M. U., Khan, S., De Matas, M., Silkstone, V., Hussain, Z., Abbasi, M., & Kousar, M. 2019. Biopolymers-based biomaterials for accelerated diabetic wound healing: a critical review. International Journal of Biological Macromolecules, 139, 975-993.
  21. Ahmad, U., Sohail, M., Ahmad, M., Minhas, M. U., Khan, S., Hussain, Z., Kousar, M., Mohsin, S., Abbasi, M. & Shah, S. A., 2019. Chitosan-based thermosensitive injectable hydrogels for controlled delivery of loxoprofen: development, characterization, and in-vivo evaluation. International Journal of Biological Macromolecules, 129, 233-245.
  22. Abbasi, M., Sohail, M., Ahmad, M., Minhas, M. U., Khan, S., Hussain, Z., Mahmood, A., Shah, S. A., & Kousar, M. 2019. Novel biodegradable pH-sensitive hydrogels: An efficient controlled release system to manage ulcerative colitis. International Journal of Biological Macromolecules, 136, 83-96.
  23. Sohail, M., Minhas, M. U., Khan, S., Hussain, Z., De Matas, M., Shah, S. A., Khan, S., Kousar, M. & Ullah, K. 2019. Natural and synthetic polymer-based smart biomaterials for management of ulcerative colitis: A review of recent developments and future prospects. Drug Delivery and Translational Research, 9, 595-614.
  24. Nadeem, N., Sohail, M., Asad, M. H. H. B., Minhas, M. U., M., & Shah, S. A., 2018. Thermosensitive hydrogels: from bench to market. Current Science, 114, 2256.
  1. Marie Skłodowska-Curie Actions Fellowship European Commission – Horizon Europe Programme Project Title: Pre-designed In situ Oncotherapeutic Nanohydrogel with Enhanced Efficacy for Glioblastoma Post-Resection (PIONEER) Funding Amount: €268,568.64 Score: 98.2% (Highly Competitive) Host Institutions: Trinity College Dublin, Ireland, and the University of Nottingham, UK Awarded for conducting advanced research on smart nanohydrogel systems for post-surgical glioblastoma therapy.
  2. Curam MedTrain⁺ (MSCA Co‑fund HORIZON‑MSCA‑2021‑COFUND‑01‑01) European Commission and CÚRAM Project Title: Pre-designed Immuno-Oncotherapeutic Nanohydrogel with Enhanced Efficacy for Glioblastoma Post-Resection Funding Amount: €153,768 Host Institutions: Trinity College Dublin, Ireland, and Glantreo Limited, Ireland.
  3. PASIFIC Marie Skłodowska-Curie Postdoctoral Fellowship Co-funded by the European Union’s Horizon Programme (MSCA No. 847639) Project Title: Biopolymer-based Enzyme-mediated Fast In Situ Injectable Hydrogels Laden with Curcumin Nanocrystals for Bone Tissue Engineering (HydroBoneReg) Role: Principal Investigator Funding Amount: €171,145.27 Awarded to develop a novel in situ forming nanohydrogel system for curcumin delivery in bone tissue regeneration.
  4. International Research Support Initiative Program (IRSIP) Fellowship Higher Education Commission of Pakistan Host Institution: University of Twente, Netherlands Role: Principal Investigator Duration: 6 months (Dec 2020 – May 2021) Funding Amount: PKR 2.5 Million Awarded to conduct part of Ph.D. research in the field of biomedical materials at an international host institution.